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Course module: 0LAUA0
0LAUA0
Project on Clinical Use of Physiological Modeling
Course info
Course module0LAUA0
Credits (ECTS)5
Category3 (Advanced)
Course typeBachelor College
Language of instructionEnglish
Offered byEindhoven University of Technology; Industrial Engineering & Innovation Sciences; Philosophy & Ethics;
Is part of
Sustainable Innovation
USE - Decisions under risk and uncertainty
Contact personprof.dr.ir. F.N. van de Vosse
Telephone4218
E-mailf.n.v.d.vosse@tue.nl
Lecturer(s)
Co-lecturer
dr. P.J. Nickel
Other course modules lecturer
Subject matter expert
prof.dr.ir. F.N. van de Vosse
Other course modules lecturer
Responsible lecturer
prof.dr.ir. F.N. van de Vosse
Feedback and reachability
Other course modules lecturer
Contactperson for the course
prof.dr.ir. F.N. van de Vosse
Other course modules lecturer
Academic year2017
Period
3  (05/02/2018 to 22/04/2018)
Starting block
3
TimeslotA: A - Mo 1-4, We 9-10, Th 5-8
Course mode
Fulltime
Remarks-
Registration openfrom 15/11/2017 up to and including 07/01/2018
Application procedureYou apply via OSIRIS Student
Explanation-
Registration using OSIRISYes
Registration open for students from other department(s)Yes
Pre-registrationNo
Waiting listNo
Number of insufficient tests-
Number of groups of preference0
Learning objectives
The student learns to combine scientific/technical knowledge, social scientific knowledge, and/or a normative framework for assessing and responding to risk, to create a clinical protocol for using a physiological model.
  • The student can read and write clinical protocols in a way that allows them to contribute actively to writing such protocols.
  • The student brings different areas of knowledge to bear on the clinical protocol: knowledge of modelling for a clinical context, knowledge of technology acceptance in a clinical setting, knowledge of norms for translational research, including norms of clinical medical ethics and norms for risk and uncertainty. In some cases students will also apply knowledge of statistics to determine the appropriate size of a clinical study.
Content
Students will meet with the project coordinators at least three times during the term for a half-hour meeting.

Additional test information:
In the initial proposal, the student group writes a project plan including a one-page summary of the envisaged project, a detailed work-plan with time breakdown per research question or design activity, and an allocation of responsibilities, and scheduled decision points and supervisory meetings, along with any supplementary information requested by the individual supervisor(s).  The reflective portfolio consists of a record of the execution of the project, analogous to a laboratory notebook, in which the work progress described in the initial proposal is documented. The portfolio should both archive the students' activities, explain and justify their choice of methodology and results, and include any additional elements agreed to with the supervisor(s). The portfolio will be reviewed by the supervisor at least once during the term.  The final product consists of a clinical protocol for introducing the clinical use of a physiological model for medical decision-making. The final product must be accompanied by a communication to a prospective user, enterprise, or societal stakeholder reflecting the main results and/or innovations related to risk, uncertainty and safety.  The final product will be assessed with input from the primary supervisor (BMT), a suitable consulting staff member from Philosophy & Ethics (ethics of biomedical technology), and if avialable an expert on clinical protocols from one of the area hospitals (e.g., Catherina Ziekenhuis).
Entrance requirements
The following course modules must be completed:
- Decisions under risk & uncertainty (0LEUA0)
- Analysis and control of risk (0LSUA0)
Entrance requirements tests
-
Assumed previous knowledge
-
Previous knowledge can be gained by
-
Resources for self study
-
Short promotional description of the course
How do you prove that a physiological model is good enough to use in clinical practice? Computational models of physiological processes are sometimes used as part of a decision-making protocol. In this project students will design a protocol for introducing such a model in a clinical setting, applying understanding of risk and uncertainty in the parameters of the physiological model, of disease risks and iatrogenic risks, and of ethical principles and social processes of technology acceptance.
Short promotional description of the course
How do you prove that a physiological model is good enough to use in clinical practice? Computational models of physiological processes are sometimes used as part of a decision-making protocol. In this project students will design a protocol for introducing such a model in a clinical setting, applying understanding of risk and uncertainty in the parameters of the physiological model, of disease risks and iatrogenic risks, and of ethical principles and social processes of technology acceptance.
Type of course in USE learning trajectory
Application
Required materials
-
Recommended materials
Reader with articles TBA
Instructional modes
Kick off

General
Tutorials for project groups, 5 students per group, more than 1 group is possible

Remark
-
Tests
Final product
Test weight70
Minimum grade5
Test typeFinal examination
Number of opportunities1
OpportunitiesBlock 3
Test duration in minutes-

Assessment
-

Remark
-

Reflective portfolio
Test weight15
Minimum grade-
Test typeInterim examination
Number of opportunities1
OpportunitiesBlock 3
Test duration in minutes-

Assessment
-

Remark
-

Initial proposal
Test weight15
Minimum grade-
Test typeInterim examination
Number of opportunities1
OpportunitiesBlock 3
Test duration in minutes-

Assessment
-

Remark
-

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