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Course module: 3MN170
Molecular biosensing
Course info
Course module3MN170
Credits (ECTS)5
Course typeGraduate School
Language of instructionEnglish
Offered byEindhoven University of Technology; Applied Physics; Molecular Biosensors for Medical Diagnostics;
Is part of
Applied Physics
Contact persondr. L.J. van Ijzendoorn
Contactperson for the course
dr. L.J. van Ijzendoorn
Other course modules lecturer
Responsible lecturer
dr. L.J. van Ijzendoorn
Feedback and reachability
Other course modules lecturer
Subject matter expert
dr. L.J. van Ijzendoorn
Other course modules lecturer
prof.dr. M. Merkx
Other course modules lecturer
Co-lecturer M.W.J. Prins
Other course modules lecturer
Academic year2017
GS2  (13/11/2017 to 04/02/2018)
Starting block
TimeslotE: E - Mo 9-10, Tu 5-8, Th 1-4
Course mode
Registration openfrom 15/06/2017 up to and including 15/10/2017
Application procedureYou apply via OSIRIS Student
Registration using OSIRISYes
Registration open for students from other department(s)Yes
Waiting listNo
Number of insufficient tests-
Number of groups of preference0
Learning objectives
  • obtaining knowledge on detection principles for in vitro and in vivo biosensing
  • understanding and being able to use principles for quantitative detection
  • ability to follow recent literature on biosensing principles
  • obtaining background for performing research in molecular biosensing
  • Content
    The course will start with an introduction on the status of and challenges in the detection of biomarkers. After an introduction in basic biochemistry and molecular recognition, the principles, quantification and applications of immunoassays will be discussed. Both label-free detection principles as well as detection with labels will be introduced. Different transducers based on optical, magnetic and electrical detection will be critically evaluated on their quantification, sensitivity and applicability.
    The challenges of in-vivo sensing will be discussed and recent research topics on both physical detection principles as well as molecular engineering will be addressed.
    Entrance requirements
    Entrance requirements tests
    Assumed previous knowledge
    Previous knowledge can be gained by
    Resources for self study
    Short promotional description of the course
    Innovatieve detectie principes maken het mogelijk om biomarkers in lichaamsvloeistoffen te volgen voor vroege diagnose en monitoring. De nieuwste fysische en biochemische technieken worden behandeld waarmee eiwitten, nucleïnezuren en metabolieten kunnen worden gemeten in een complexe moleculaire omgeving. Zowel fundamentele principes als detectie in en buiten het lichaam worden bediscussieerd.
    Short promotional description of the course
    Innovative sensing principles enable quick and quantitative detection of biomarkers in body fluids for early diagnosis and monitoring. New quantitative physical and biochemical technologies will be discussed to detect proteins, nucleic acids and metabolites in a complex molecular environment. Both fundamental principles and in-vitro and in-vivo sensing applications will be evaluated.
    Bachelor College or Graduate School
    Graduate School
    Required materials
    Recommended materials
    Lecture slides and recent articles from literature as well as exercises provided for selfstudy
    Instructional modes
    Studio Classroom

    7 weeks of 4 hours studio classroom

    Written examination
    Test weight100
    Minimum grade-
    Test typeFinal examination
    Number of opportunities2
    OpportunitiesBlock GS2, Block GS3
    Test duration in minutes180



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