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Course module: 8RB00
8RB00
Molecular cell biology
Course info
Course module8RB00
Credits (ECTS)5
Category2 (Deepening)
Course typeBachelor College
Language of instructionDutch
Offered byEindhoven University of Technology; Biomedical Engineering; Chemical Biology;
Is part of
Biomedical Engineering
Pre-master program Biomedical Engineering
Chemical Engineering and Chemistry
Medical Sciences and Engineering
Contact personprof.dr.ir. L. Brunsveld
Telephone2870
E-maill.brunsveld@tue.nl
Lecturer(s)
Contactperson for the course
prof.dr.ir. L. Brunsveld
Other course modules lecturer
Responsible lecturer
prof.dr.ir. L. Brunsveld
Other course modules lecturer
Subject matter expert
prof.dr.ir. L. Brunsveld
Other course modules lecturer
Co-lecturer
prof.dr. M. Merkx
Other course modules lecturer
Academic year2017
Period
2  (13/11/2017 to 04/02/2018)
Starting block
2
TimeslotC: C - Tu 1-4, Fr 5-8, Fr 9-10
Course mode
Fulltime
Remarks-
Registration openfrom 15/06/2017 up to and including 15/10/2017
Application procedureYou apply via OSIRIS Student
Explanation-
Registration using OSIRISYes
Registration open for students from other department(s)Yes
Pre-registrationNo
Waiting listNo
Number of insufficient tests-
Number of groups of preference0
Learning objectives
After passing the course, the student has insight in:
  1. The molecular biology of DNA based molecular mechanisms and the structure and complexity of the genome and can describe DNA related cell biological molecular processes.
  2. DNA and RNA manipulation mechanisms and can describe polynucleotide manipulation processes.
  3. The molecular cell biological processes of gen regulation and can describe these processes and the consequences of changes.
  4. Cellular regulation mechanisms and signal transduction and can describe these processes and the consequences of changes.
  5. The functioning of the control of the cell cycle and apoptosis and can describe these processes and the consequences of changes.
  6. Molecular cell biological processes and can integrate this when describing these processes involved cancer.
  7. The molecular basic principles of the functioning of the immune system and can describe these processes.
Content
The cell is a complex system where regulation is a key event, leading to cell diversity and cell differentiation. In this lecture series we will discuss the most important functions and organelles in the cell. Subjects will include gene regulation, signal transduction, the immune system, and cell division. Also the effects of defects in these processes, which can lead to e.g. cancer, will be treated. Knowledge of genes and molecular techniques makes it possible to manipulate DNA in order to influence basic cellular processes, which can lead to a better understanding of the functioning of cells and organisms. Molecular biological topics that will be discussed are:
  • Cloning and characterisation of DNA and genes
  • DNA mutagenesis
  • RNA interference (RNAi)
  • Micro-array techniques
  • Gene therapy
  • Transgenic cells and organisms
Entrance requirements
Entrance requirements tests
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Assumed previous knowledge
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Previous knowledge can be gained by
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Resources for self study
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Bachelor College or Graduate School
Bachelor College
Required materials
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Recommended materials
Molecular Biology of the Cell, Sixth edition; Bruce Alberts et al. Publisher: Garland Science 2015. ISBN-13: 978-0815344643
Instructional modes
Guided selfstudy

General
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Remark
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Lecture

General
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Remark
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Lecture

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Remark
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Tests
Written examination
Test weight100
Minimum grade6
Test typeFinal examination
Number of opportunities2
OpportunitiesBlock 2, Block 3
Test duration in minutes-

Assessment
-

Remark
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