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Course module: 8VM20
Cardiac function
Course info
Course module8VM20
Credits (ECTS)5
Course typeGraduate School
Language of instructionEnglish
Offered byEindhoven University of Technology; Biomedical Engineering; Cardiovascular Biomechanics;
Is part of-
Contact P.H.M. Bovendeerd
Contactperson for the course P.H.M. Bovendeerd
Other course modules lecturer
Responsible lecturer P.H.M. Bovendeerd
Other course modules lecturer
Subject matter expert P.H.M. Bovendeerd
Other course modules lecturer
Co-lecturer M.C.M. Rutten
Other course modules lecturer
Academic year2017
GS2  (13/11/2017 to 04/02/2018)
Starting block
TimeslotE: E - Mo 9-10, Tu 5-8, Th 1-4
Course mode
Registration openfrom 15/06/2017 up to and including 15/10/2017
Application procedureYou apply via OSIRIS Student
Registration using OSIRISYes
Registration open for students from other department(s)Yes
Waiting listNo
Number of insufficient tests-
Number of groups of preference0
Learning objectives
1. Understanding of the relation between hemodynamics and cardiovascular properties
2. Understanding of the origin and propagation of the action potential, and the ECG
3. Understanding of the mechanical properties of passive and active cardiac tissue
4. Understanding of the relation between cardiac structure and cardiac deformation
5. Understanding of the changes in cardiac deformation in case of infarction or conduction disorders
6. Understanding of cardiac regulation, growth and remodeling
7. Insight in the role of models of heart and circulation in the clinic
Cardiac pump function is the result of the interaction between the heart and the vascular system. Cardiac properties involved are geometry, orientation of the myofibers in the cardiac wall, mechanical and electrical tissue properties, and coronary perfusion. Relevant vascular properties are valve function, and vascular compliance and resistance. To fulfill the changing oxygen demand of the body, cardiac and vascular properties are time dependent, both on the short term, through regulation, and on the long term, through growth and remodeling.

In this course cardiac pump function is analysed through mathematical models of the underlying properties and processes. These models provide insight into the basis of normal pump function, in the way in which pathological changes in heart and vessels affect cardiac pump function, and in the adaptive response of the heart to these changes. They also provide insight in the way in which clinically observable indicators of decreased pump function can be translated into the underlying pathology at tissue level, which opens up the path to model assisted decision making in the clinic.
1. The heart in the circulatory system
2. Cardiac electrical activity
3. Myocardial mechanical properties
4. Cardiac mechanics
5. Cardiac growth and remodeling
6. Patient specific modeling
Entrance requirements
You must have completed the final examination bsc program exam
Entrance requirements tests
Assumed previous knowledge
• 8MB00 - Continuum mechanics
• 8VB00 - Transport Physics
• 8MC00 - Numerical analysis of continua
Previous knowledge can be gained by
Resources for self study
Bachelor College or Graduate School
Graduate School
Required materials
Recommended materials
Instructional modes
Guided selfstudy




Written examination
Test weight100
Minimum grade6
Test type-
Number of opportunities2
OpportunitiesBlock GS2, Block GS3
Test duration in minutes-



Kies de Nederlandse taal