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Course module: 8WC00
8WC00
Regeneration
Course info
Course module8WC00
Credits (ECTS)5
Category3 (Advanced)
Course typeBachelor College
Language of instructionDutch, English
Offered byEindhoven University of Technology; Biomedical Engineering; Soft Tissue Engineering and Mechanobiology;
Is part of
Biomedical Engineering
Medical Sciences and Engineering
Contact personprof.dr. C.V.C. Bouten
Telephone3006
E-mailc.v.c.bouten@tue.nl
Lecturer(s)
Contactperson for the course
prof.dr. C.V.C. Bouten
Other course modules lecturer
Responsible lecturer
prof.dr. C.V.C. Bouten
Other course modules lecturer
Co-lecturer
dr. D. van Geemen
Other course modules lecturer
Co-lecturer
dr. C.M. Sahlgren
Other course modules lecturer
Academic year2017
Period
2  (13/11/2017 to 04/02/2018)
Starting block
2
TimeslotC: C - Tu 1-4, Fr 5-8, Fr 9-10
Course mode
Fulltime
Remarks-
Registration openfrom 15/06/2017 up to and including 15/10/2017
Application procedureYou apply via OSIRIS Student
Explanation-
Registration using OSIRISYes
Registration open for students from other department(s)Yes
Pre-registrationNo
Waiting listNo
Number of insufficient tests-
Number of groups of preference0
Learning objectives
After passing the course, the student has insight in:
  1. The basic principles of growth, differentiation, homeostasis, and adaptation of specialized tissues of the human body at the molecular level, the cellular level and tissue level and can reproduce these basic principles.
  2. The basic principles of tissue damage, repair, regeneration, and remodeling at molecular, cellular level and tissue level and can reproduce these basic principles.
  3. Pathological (deregulated) repair and tissue formation and can describe homeostatic imbalance.
  4. The above-mentioned principles and can apply and integrate these into the field of regenerative medicine, combining principles from basic biology, tissue homeostasis and pathology with engineering strategies.
Content
The course is built on four pillars that treat:
  1. Growth, differentiation, and regeneration of specific tissues and during different stages of development
    • Foetal development, growth, maintenance of adult tissues and senescence.
    • Stem cells, proliferation, differentiation in various tissues and stages of development.
    • Maintenance and regeneration of various tissues (blood, skin, gut, muscle, bone, nerve)
  2. Damage, repair, adaptation and remodelling of tissue
    • Triggers for tissue damage and response to damage, reversible versus irreversible cell damage.
    • Inflammation and wound healing
    • Repair versus regeneration
  3. Pathological repair, adaptation and remodelling
    • Atherosclerosis, fibrosis, cancer
  4. Principles and application of regenerative medicine
Entrance requirements
Entrance requirements tests
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Assumed previous knowledge
• 8TA00 - Cell and tissue
• 8RB00 - Molecular cell biology
• 8SC00 - Materials science
• 8TB00/8MB00 - Continuum mechanics
Previous knowledge can be gained by
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Resources for self study
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Short promotional description of the course
De weefsels in het menselijk lichaam zijn voortdurend onderhevig aan verandering. Tijdens groei, aanpassing aan nieuwe omstandigheden, of als gevolg van schade of ziekte kunnen samenstelling en structuur van het weefsel veranderen, of treden verschuivingen op in differentiatie en functie van het weefsel. Het lichaam kent hiervoor een aantal strategieën die we kunnen nabootsen of gebruiken bij nieuwe medische behandelmethoden, zoals de regeneratieve geneeskunde.
Short promotional description of the course
The various tissues of the human body show an intriguing adaptive capacity. Their composition, structure, differentiation and function may change as a consequence of growth, adaptation to environmental cues, injury, or disease. The body knows several inherent strategies to cope with these changes, which can be used or mimicked for new clinical treatment modules like regenerative medicine.
Required materials
Alberts et al., Molecular Biology of the Cell, Garland Science, 6th edition, ISBN 9780815344322
Studyguide
Recommended materials
Rubin’s Pathology, Lippincott Williams & Wilkins, ISBN 9781451183900 (only several chapters will be used)
Instructional modes
Guided selfstudy with notebook / PC

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Lecture

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Tutorial

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Tests
Paper
Test weight30
Minimum grade-
Test typeInterim examination
Number of opportunities2
OpportunitiesBlock 2, Block 3
Test duration in minutes-

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Written examination
Test weight70
Minimum grade5
Test typeFinal examination
Number of opportunities2
OpportunitiesBlock 2, Block 3
Test duration in minutes-

Assessment
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